The aorta, the main artery in the human body, is located in the left ventricle of the heart. The aorta begins at the top of the left ventricle. The descending aorta starts after the arch of the aorta and ends by splitting into two great arteries that lead to the legs.
The esophagus, a muscular tube connecting the pharynx (throat) with the stomach, runs behind the trachea (windpipe), and heart, and in front of the backbone or spine.