A. True. Based on the history of marijuana and other cannabis products, Marijuana was the number-one cash crop in the united states prior to 1890. Marijuana is a depressant and does not contain nicotine. It is a schedule I controlled substance, according to U.S. federal regulations where there is approximately 77% of illicit drug users smoke marijuana. The use of marijuana for medicinal purposes is illegal in the U.S but legal in Canada. The "reverse tolerance" turns out to be due to variations in the manner in which the drug is ingested is one of the long-term effect of Marijuana.