Answer: B) With understanding.
Step-by-step explanation: an affix is an addition to the base form or stem of a word in order to modify its meaning or create a new word, it can be at the beginning of the word (prefix) or at the end of the word (suffix). Knowing that the meaning of the prefix "com" is "with," the most likely meaning of the word "compassionately" is the corresponding to option B: with understanding, with compassion.