The second alternative is correct.
Gender dysphoria occurs when a person does not identify with their biological sex, which is male or female. It is a situation in which the person's brain, which defines its gender identity does not match with biological sex. This is explained by science, which describe that dysformia is caused during the gestational process.
People with gender dysphoria often suffer from failing to identify with their body, so they need a treatment to make the diagnosis and possibly the adjustment through surgery. They are transsexual people. These people are very discriminated against by society, so it is extremely important to support and respect them.