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Which factor in the ohio valley caused british-american relations to deteriorate?

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Because of the Indians.
User SAHIL SINGH SODHI
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In 1763 King George III made a Royal Proclamation that forbade American colonists from settling west of the Appalachian Mountains and no longer recognized land claims. This territory was attached to the royal crown province of Quebec and given to Indian tribes who were in conflict with the colonists.
User Paul Meems
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