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Hypothesize what potential impact a mutated egfr allele will have on a cell

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Epidermal Growth Factor Receptor or EGFR is a factor that controls growth in epidermal cells. EGFR will induce division of cells so they are important in cell growth. In there is a mutated EGFR allele, the synthesis of EGFR might be disrupted causing increase/decrease to the growth factor.
If the mutation causing an increase of EGFR then you can hypothesize that the person will be increased risk to developing a cancer.
User James Rocker
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Mutated EGFR can lead to cancer (especially lung cancer).

A mutation in EGFR is associated with uncontrolled tumor growth, which can accelerate cancer progression.

Epidermal Growth Factor Receptor (EGFR) receptors are found on the surface of tumor cells and their role is to send a growth signal to the nucleus of the cell. Some lung cancer tumors may contain a mutation in their DNA that affects the EGFR. The tumor is said to be "positive for EGFR mutations".

Tumor cells with EGFR mutations are highly sensitive to cancer treatments called "Targeted Therapies" or "EGFR Tyrosine Kinase Inhibitors".

User Simon Cozens
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