Although both settlements suffered from diseases, starvation and conflict with the Natives in America, there was one significant difference between the settlement of Jamestown and the settlement of Plymouth. The colonists at Plymouth were Dutch who had previously lost their English heritage because of religious persecution that forced them to move to Holland. However, they did not feel satisfied with this country culture, so they moved to the New World in search of religious freedom. On the contrary, the colonists at Jamestown decided to leave their native country, England, motivated by economic reasons as well as financial profit from their investment in shares of the Virginia Company of London. Consequently, option "D" is the correct one.