111k views
4 votes
Approximately 1.0g of caffeine will dissolve in 28ml of methylene chloride and in 46ml of water. calculate the distribution coefficient of caffeine in this solvent system.

1 Answer

3 votes
K D = 1.0g/ 28 ml 0.0357

-------------- = ---------- = 1.65

1.0 g/46 ml 0.0217

is the distribution coefficient of caffeine in this solvent system