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If the citric acid cycle was interrupted after the reaction that forms citrate, predict how this would affect the total amount of atp generated per glucose molecule

User SamYoungNY
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The amount of ATP produced would go from 38 ATP down to 14 ATP per glucose molecule. This answer is true because up to the conversion from Acetyl-CoA to Citrate, the cell has produced 14 ATP molecules. 8 gross ATP and 2 Pyruvic acid molecules are produced during Glycolysis. The Pyruvic acid to acetyl CoA conversion nets another 3 ATP. Since there are two Pyruvic acid molecules, that is a total of 6 ATP. Combining glycolysis (8 ATP) and the first reaction in the citric acid cycle (6 ATP), that is a total of 14 ATP produced.
User Maarten Buis
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