The correct answer is B) We depend on them to provide us with a supply of food and fresh water.
The statement that best describes how humans most often depended on rivers to meet our needs is "We depend on them to provide us with a supply of food and fresh water."
Since the very beginning, humans have depended on rivers to survive. Rivers are a source of fresh water and food. Ancient civilizations such as Sumeria and Egypt settled in next to rivers. Sumer settled in the middle of the Euphrates and Tigris Rivers in the Middle East region. Egypt settled in next to the Nile River in North Africa. And both civilizations became very prosperous.