Question

Uppose you are a research assistant in a lab studying dna- binding proteins. you have been given the amino acid se- quences of all the proteins encoded by the genome of a certain species and have been asked to find candidate proteins that could bind dna. what type of amino acids would you expect to see in the dna-binding regions of such proteins? why?

Answer 1

The type of amino acids I would expect to see in the DNA binding regions of such proteins are AMINO ACIDS THAT ARE POSITIVELY CHARGED AT pH 7.
This is because, DNA is a negatively charged molecule, for binding to take place on its surface, the other molecule must be positively charge, in order for them to attract each other.