The hormonal cascade of the fight or flight response which is the emotional aspect of the stress reponse propogates through three main steps
Stimulation of the hypothalamus by the amygdala causes the release of corticotrophin-releasing factor (CRF).
CRF then stimulates the pituitary gland causing release of adrenocorticotrophin (ACTH) into the bloodstream
ACTH travels through the bloodstream and stimulates the adrenal glands causing the release of ephinephrine (adrenaline) and glucocorticoids including cortisol.
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