Answer:
Yes, changes in scientific knowledge occur often
Step-by-step explanation:
Scientific knowledge is always under several tests to see if new variables for a specific phenomenon fit with the earlier prediction from a specific model (e.g theories), so it is very common that changes in what is known occur with certain frequency.
A look in the history of science gives several examples of this changes. For example, in the field of physical particles there was a time when it was believed that protons and neutrons were fundamental particles. Then, further studies and experiments demonstrated the presence of ups and downs¹ inside protons and neutrons. Even earlier than that, it was thought that the atom was indivisible, but experiments like the cathode ray showed how smaller particles (electrons) exist inside of it.
Another example is the theory of relativity, in which every of its predictions has been proved in a extend range of scenarios (for example the case of gravitational waves²).
¹Ups and downs: Fundamental particles.
²Gravitational Waves: They are ripples in the curvature of space-time, created by the collision or explosion of object with high masses.