Answer:
The mutation
Step-by-step explanation:
The mutation is characterized by changes in the DNA nitrogen base code that lead to new versions of the genes. This condition may produce new characteristics in mutation carriers. When a mutation occurs the whole organism is compromised because an error in the nitrogenous bases of DNA causes errors in transcription and translation processes, causing proteins generated from DNA code to become defective and cause harmful changes to the organism.
In other words, we can say that a mutation is more harmful than errors in transcription. This is because a mutation compromises the whole functioning of the body, while errors in transcription compromise only one protein of a given cell.