Final answer:
The spread of the bubonic plague in the 14th century was driven by long-distance trade routes like the Silk Road and compromised urban living conditions that facilitated the proliferation of the disease.
Step-by-step explanation:
Two major socioeconomic factors contributed to the spread of the bubonic plague, commonly referred to as the Black Death, throughout China and Western Europe in the 14th century. First, the expansion and use of long-distance trade routes such as the Silk Road significantly facilitated the spread of the disease, as the movement of merchants and travelers allowed for the transmission of infected fleas and rats to new regions. Secondly, changing social conditions, such as the growth of urban centers with poor sanitation and overcrowded living conditions, created ideal environments for the proliferation of the plague. These factors, alongside technological and cultural exchanges during this era, often through the movement of soldiers and refugees, exacerbated the pandemic's reach, decimating populations and leading to profound economic and social changes.