Body defenses that respond to generalized tissue damage and many common pathogens are referred to as nonspecific mechanisms. It refers to the innate immune system. It is an essential system of the overall immune system of the body as it consists of cells and mechanisms that would defend the body from infection. Example would be the skin. It is the very first line of defense of the body against any foreign materials. It acts an almost impenetrable barrier to pathogens keeping them outside. The skin has oils and sweat making it acidic so it inhibits the growth of a number of microorganisms.