Answer:
Gender Dysphoria
Step-by-step explanation:
Science has shown that gender formation occurs during pregnancy and usually accompanies biological genital development. However, in some cases an exception occurs in which people are born with certain biological genitalia but have a different gender identity. It's transsexual people.
The sign of transsexuality is exactly what is described in John's case. The person does not identify with the biological genital. Transsexuals are distinct gendered individuals trapped in the opposite biological body. These people suffer from it and must be evaluated and dealt with to correct the problem that afflicts them. And, of course, they must be accepted and respected by society.