Question

A patient experiences chronic gastritis with a loss of parietal cells due to atrophy. the nurse determines that the patient is at risk for a complication associated with the loss of the parietal cells. which diagnostic test will assist in making this determination?

Answer 1

Answer: Biopsy (endoscopy)

Explanation: Chronic gastritis with a loss of parietal cells due to atrophy (i.e degeneration of cells) is usually caused by bacterial infection (often H. Pylori).

Parietal cells are epithelial cells that line the gastric and secretes hydrochloric acid (HCl) and intrinsic factor in the stomach.

The best approach to diagnose the presence or loss of parietal cells is through biopsy. It is carried out by insertion of an endoscope through the mouth and down into the stomach to pick stomach cells samples. Then, the abundance and stability of the parietal cells is observed.

Answer 2

The diagnostic test that will further determine if a patient is experiencing chronic gastritis is through testing of vitamin B12 deficiency. When a patient is experiencing the condition, the body is not able to absorb the vitamin. Another test is blood iron test. Malabsorption of iron is also a direct indicator for chronic gastritis which is caused by the loss of parietal cells due to atrophy.