Question

Genetic disorders can result when chromatids fail to separate properly. During which phase is this problem most likely to occur?

A. Prophase
B. Telophase
C. Anaphase
D. Metaphase

Answer 1

More then likely C. Anaphase its when the sister chromatids separate to opposite poles 

Answer 2

C). Anaphase

Step-by-step explanation:

During the division of a cell, either by Mitosis or Meiosis, the nuclear material separates into individual daughter cells (opposite) before the cytoplasmic content of the cell divides in CYTOKINESIS. Mitosis and Meiosis consists of different stages characterized by specific occurrences. The stages in mitosis and meiosis include Prophase, Metaphase, Anaphase and Telophase. The Prophase is characterized by condensation of chromatin into visible chromosomes.

The metaphase is characterized by alignment of the sister chromatids (replicated chromosomes) at the equator of the cell. The Anaphase stage is where the separation of individual chromatid into opposite poles of the cell occurs. This process is called KARYOKINESIS.

Hence, a genetic disorder that occurs due to the failure of chromatids to separate called NONDISJUNCTION will occur in the Anaphase stage of the division process.