Answer:
0
Explanation:

To simplify we need to combine like terms
Here all terms have variable xy^3
So all terms are like terms
To combine all the like terms, we need to add the coefficient of all the terms
For example 5x + 2x is 7x
-xy^3 is -1xy^3

(-3 + 7 -1-3) xy^3
0xy^3
0 times anything is 0
So answer is 0