Question

Which of these mechanisms do cytotoxic t (tc) cells use to destroy a target--that is, deliver a lethal hit?

Answer 1

Cytotoxic T cells use two basic mechanisms to destroy target cells: 1. Cytotoxic T cells release perforins which create pores on the target cells and granzymes which stimulate the apostosis of the target cells by exocytosis. 2. Cytotoxic T cells bind specific membrane receptors on the target cells and stimulate apostosis process which eliminate the target cells.

Answer 2

The answer to this question is PERFORATION OF THE MEMBRANE. Actually, the Cytotoxic T cells are the ones that kill cancer cells, and other cells that are infected or damaged. What this cytotoxic T cells do is that they release cytotoxins and this would result to apoptosis or cell death. How this is effectively done is through the perforation of the membrane.