Your expression, as typewritten, is a bit ambiguous. Did you intend for 48t7 u4 v to be the denominator? If so, please enclose 48t7 u4 v inside parentheses.
Then your -20t5 u2 v3 /48t7 u4 v
becomes
-20t5 u2 v3
----------------- which can be separated for easier reduction:
(48t7 u4 v)
(-20/48) (t^5 / t^7) (u^2 / u^4) (v^3 / v)
Reduce the quantity within each set of parentheses:
(-5/12) (1/t^2) (1/u^2) (v^2)
Please note: You must use " ^ " to denote exponentation. u5 is ambiguous; you mean u^5 = "u to the fifth power."