Answer: Option (D) is the correct answer.
Step-by-step explanation:
In a nuclear reaction, subparticles like protons and neutrons are involved in a reaction. So, basically changes in the nucleus of an atom occurs.
This is because in a nuclear reaction either two nuclei combine to form a larger nuclei different from its parent atom or nucleus of an atom dissociates into different atoms.
For example,
is a nuclear fusion reaction.
Whereas in a chemical reaction exchange of electrons occur or we can say electrons are involved in chemical reactions.
For example,

Thus, we can conclude that out of the given options, there is a change in the nucleus distinguishes a nuclear reaction from a chemical reaction.