Question

How did Watson and Crick determine base pairing?

A.)they analyzed the work of Phoebus Levene.
B.)They used Chargaff's rule to fit the bases together.
C.)They broke the hydrogen bond.
D.)They observed the pairing under a microscope.

Answer 1

Their model of the DNA molecule showed that the hydrogen bonds could create a nearly perfect fit between nitrogenous bases along the center of the molecule. But the bonds could only form between adenine and thymine, and between cytosine and guanine.