Question

Fibrodysplasia ossificans is a disease in which fibrous tissue, such as ligaments and tendons, are incorrectly converted to bone when damaged. Over time, the body loses flexibility as joints become locked in one position. Based on this information, which of the following would be unusually high in a person suffering from fibrodysplasia ossificans? (2 points)

Osteoclast activity in connective tissue

Osteoclast activity in muscle tissue

Osteoblast activity in connective tissue

Osteoblast activity in muscle tissue

Answer 1

osteoclast activity in the muscle tissue

Answer 2

Answer: Osteoblast activity in connective tissue.

Step-by-step explanation:

• Fibrodysplasia ossificans is an autosomal dominant disorder caused by a mutation in the gene ACVR1 which affects the connective tissue of the body.

• In this disease, there is ossification of the fibrous tissue which causes several disabilities.

• The ossification of the bone mainly results from abnormally high osteoblast activity in connective tissue after minor trauma to the body.