Final answer:
Francisco Madero is best known for leading the Mexican Revolution against Porfirio Díaz and advocating for social and political reforms in Mexico.
Step-by-step explanation:
Francisco Madero is best known for leading the Mexican Revolution against the dictatorial regime of Porfirio Díaz. He was a liberal politician who advocated for social and political reforms in Mexico. Madero's most significant accomplishment was his role in overthrowing Díaz and initiating the period of political and social change in Mexico known as the Mexican Revolution. He became the President of Mexico in 1911 after Díaz's resignation, but his presidency was short-lived, as he was assassinated in 1913.