In healthcare providers, most infectious disease exposure occurs due to sharp injuries caused by penetration of blades, needles, scalpels, into the skin. These instruments when contaminated with an infected patients' blood, can cause more than 20 diseases including HIV, and hepatitis. These injuries are also called as percutaneous injuries. Following such injury, the wound should be held under running water, dry, and cover with waterproof dressing. The person should also consult a medical advice on an urgent basis.