Answer:
Option). Inflammation, which result from histamine release
Step-by-step explanation:
Inflammation can be defined as an immune response of body against harmful agents, such as damaged cells, pathogens, or other irritants. It is a protective response of immune system, which involves blood vessels, inflammation mediators, and white blood cells.
Redness, pain, heat, and swelling are common signs of inflammation. Redness is caused by the increased diameter of blood vessels at the site of infection, while the pain is caused by inflammatory chemicals, such as histamine that activates nerve ending.
Thus, the correct answer is option). third.