Answer:
Carbon dioxide is produced as waste product of cellular respiration in the body.
It is transported in the dissolved from in the blood.
It is transported by three mechanisms:
1. About 10% of carbon dioxide is transported in the dissolved form in the RBC.
At tissue level, the concentration of carbon dioxide is higher due to which it easily diffuses into the RBC and transported to the alveolar site.
2. Almost 20-30% is transported with the help of haemoglobin as carbamino-hemoglobin.
Hemoglobin can bind to both oxygen as well as carbon dioxide in a reversible manner depending on the partial pressure of both. Due to high partial pressure of carbon dioxide at tissue level, hemoglobin dissociates from oxygen and binds to carbon dioxide.
3. As bicarbonate ion: The carbon dioxide in RBC reacts with water and forms HCO₃⁻ & H⁺. The reaction is catalyzed by carbonic anhydrase.
At alveolar site, the reactions are reversed due to high partial pressure of oxygen and low partial pressure of carbon dioxide.
The dissolved carbon dioxide diffuse down the concentration gradient into alveolar site. Similarly, hemoglobin also dissociates from carbon dioxide and attaches with oxygen. Lastly, the same enzyme reverses the reaction and forms carbon dioxide and water from HCO₃⁻ & H⁺.