Question

Two simple machines that are part of a bicycle are a(n)

Answer 1

Levers: Shifters, crankset (the pedal levers), derailleurs, handlebars, freewheel assembly, brakes.
Wheel and axel: The wheels, pedals, crankset, cassette.
Pulleys: Parts of the shifting mechanisms, braking mechanisms, and the drive train (chain on gears).
Screws: (Hold parts together).
Wedges: The teeth on the gears.

Answer 2

Wheel and axle but you can also add the lever as a third:)