Let five moles of oxygen are required to react with 2 moles of acetylene. So, doing a rule of three, we are going to obtain :
5 moles of Oxygen => 2 moles of C2H2
? O2 => 1 mole of C2H2
1.0 mole C2H2×(5 moles O2/2 moles of C2H2) = 2.5 moles of O2
So, the answer is 2.5 moles of oxygen are required to react with 1 mole of acetylene.