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He ________ is located deep within the brain, and it includes structures such as the substantia nigra and ventral tegmental area.

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The answer that fits the given blank above is MIDBRAIN. The MIDBRAIN is in the deep areas of the brain and includes the parts such as the substantia nigra, reticular formation and the ventral tegmental area. The midbrain is responsible for hearing, vision, sleep/wake, arousal, motor control and the regulation of temperature.
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