The third alternative is correct (C).
The Colombian exchange originated from the exchanges between the old world and the new world that happened in the context of the great navigations. It was the formation of a market network between various parts of the globe.
In terms of food, the sending of cultivated vegetables originating in America to be produced in Europe, Asia and Africa has altered the dietary habits of the populations of these regions.
In the sanitary aspect, the arrival of the Europeans to the Americas was accompanied by a series of microorganisms and diseases for which the American Indians had no antibodies, which generated a great number of indigenous deaths by diseases that were simple for the white men.