Answer:
The correct answer is - the active site of the enzyme-modified so it can fit the substrate and begin the chemical reaction.
Step-by-step explanation:
The induced-fit model of the enzyme is a hypothesis that tries to explain the interaction between enzyme and substrate.
It is a theory that refines lock and key theory by suggesting that if an enzyme comes in touch with a particular substrate, the active site of enzyme molds or changes its shape to fit the substrate. The properly fit enzyme-substrate complex initiates the chemical reaction.
Thus, the correct answer is - the active site of the enzyme modified so it can fit the substrate and begin the chemical reaction.