Final answer:
For a second-degree burn larger than 2 to 3 inches, you should wrap the area in a clean, dry bandage and call 911 due to the potential severity and risk of infection and deeper tissue damage.
Step-by-step explanation:
If a second-degree burn is larger than 2 to 3 inches, an appropriate first-aid response is to wrap the burned area loosely in a clean, dry bandage. It is crucial to avoid submerging the burn in cold water as it may cause further damage. Elevating the burned area can help reduce swelling, but more importantly, due to the potential severity of a large second-degree burn, it is essential to call 911 or seek professional medical assistance immediately. This prompt action is required to avoid complications such as infection or deeper tissue damage. Furthermore, watching for increased redness, swelling, and pain is important for preventing infection.