I would not use abreva on a pimple, because abreva is designed to get rid of cold sores. Cold sores are made up of a different bacteria than pimples. If you use the abreva on a pimple it may sting, itch, become red and dry, or it may become scab-like. I would recommend to use Listerine on pimple if you don't have acne medication. I hope this helps! : )