We have to consider that the DNA is first transcribed into pre mRNA in the nucleus of the cell by the RNA polymerase. After this process, the non-coding fragments (introns) of the molecule are spliced by ribonucleoproteins (snRNP). Eventually, each end of the pre mRNA is modified, being a modified nucleotide named CAP joined to the 5' end, and a polyA (poly Adenine) tail at the 3' end before the now matured mRNA gets out of the nucleus to the cytoplasm.
At this point, the mRNA will be recognized by ribosomes, which will synthesize each group of three nucleotides (codons) into amino acids in a process called translation, by the action of tRNA, and finally joined into a new protein.
Note that A, P, and E are sites of the ribosomes, being A the position where first arrives the mRNA.