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Leonardo was fascinated with human anatomy. He conducted medical research in hospitals in Florence and Rome. His notebooks are filled with sketches of bones, muscles, and organs. For example, he made detailed drawings of a human fetus and a human heart.

Which sentence is the topic sentence?
 

He conducted medical research in hospitals in Florence and Rome.

His notebooks are filled with sketches of bones, muscles, and organs.

Leonardo was fascinated with human anatomy.

For example, he made detailed drawings of a human fetus and a human heart

User Kanan
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I would probably say the third one: Leonardo was fascinated with anatomy. Hope this helped! 
User Miroslav Saracevic
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Leonardo was fascinated with human anatomy

User Sudhanshu Mishra
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