Question

Flag questionTransfer RNAs (tRNA) are produced through transcriptionof tRNA "genes" (DNA).It is of course essential that the tRNAs produced havecorrect ribonucleotide sequences so that (i) they arerecognised by the correct aminoacyl tRNA synthetase and(ii) they have an anticodon that matches them to thecorrect mRNA codon during translation.ESTSAssume the DNA encoding one of the tRNAs for the aminoacid tryptophan has been mutated and instead of itsanticodon sequence reading 5'-CCA-3' (correct), it nowreads 5'-TCA-3' (incorrect).What will be the effect on protein synthesis? Explainbriefly.TEEK 11CEK 11

Answer 1

It would depend on whether the modified codon code for the same amino acid or not. If it does not code for the same amino acid, then the protein would be different, and in some cases, it can cause a problem with its function, mostly if this modification is found on the interaction site of the protein with other components.