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The most commonly abused chemical substance is:

tobacco products
alcohol
marijuana
cocaine

User Ketsy
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The most commonly abused is alcohol
User Chansey
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The most commonly abused chemical substance in alcohol. 17.6 million people, that is one in every 12 adults, suffer from alcohol abuse or dependence along with several million more who engage in risky, binge drinking patterns that could lead to alcohol problems.
User Dottedquad
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