¿Cómo es Rogelio? translates to "How is Rogelio?" The options are as follows.
A) Está en la biblioteca - "He/She is at the library"
B) Es de España - "He/She is from Spain"
C) Enfermo - "He is sick"
D) Tiene pelo negro - "He/She has black hair"
The only option which it makes sense to answer with is option C:
"How is Rogelio?"
"He is sick."
Answer:
C) Enfermo