Answer:
The Factor that most affects drug absorption s the Lipid solubility of the drug
Explanation:
For a drug to accomplish its pharmacological function, it needs to suffer absorption mechanisms.
Most drugs, those that do not act locally, need to be correctly concentrated in their action sites or target sites. The first step is absorption.
This involves the obligated pass through the semipermeable plasmatic membrane to finally get in the blood. In blood, the drug moves, distributes, metabolizes, and the unaltered molecules are excreted.
There are different mechanisms in which drugs can cross the membrane that depends on the drug type. Depending on the effects of these mechanisms, there will be a more or less concentrated drug at the target sites.