Answer:
The answer to the question: What will happen to the frequency of the recessive allele for the HbS gene when there is an outbreak of Malaria? is, that especially in regions where Malaria is a norm, like Africa, people tend to express their HbS gene, typical of sickle cell anemia, and which protects them from malaria, more, than those who have not been exposed to it.
Step-by-step explanation:
Malaria is a parasitic infection of the red blood cells that can be lethal depending on who is infected and his/her genetic characteristics. Especially depending on whether a person´s blood cells present heterozygote characteristics or homozygous ones, and the structure of their HbS, these cells will act differently when confronted by a parasite like malaria, and the body will be able to effectively respond to the infection, or not, at all. In people who historically have been constantly faced by the exposure to malaria, it is more common to find that the expression of the recessive allele HbS increases, protecting them from dying of malaria.