Answer:
The sentence that best describes Douglass’s opinion about slavery is "Slavery is degrading to both the slaveholder and the enslaved."
Step-by-step explanation:
This excerpts has lines that support the idea that "Slavery is degrading to both the slaveholder and the enslaved." such as "Slavery soon proved its ability to divest her of these excellent qualities, and her home of its early happiness" where we can see that this is affecting not only the slaves but also the people who interact with them sometimes making them insensible to others necessity or pain.