Question

Josh was a participant in a clinical study to determine how much thiamin cures beriberi, the vitamin's deficiency disease. during the study, josh consumed only a formula diet that was nutritionally complete, except it did not contain thiamin. within a few weeks, josh developed beriberi. at that point, researchers gave 0.20 mg thiamin to josh each day for a week, but his signs and symptoms of beriberi remained. in the weeks that followed, the scientists continued to increase josh's intake of the vitamin by 0.2 mg/week. after a week of taking 0.6 mg of thiamin/day, josh reported feeling much better. based on this information, the researchers concluded that josh's

Answer 1

Answer: RDA for thiamine was 0.6mg/day

In Josh case, the researcher concluded that 0.6mg of thiamine per day is needed by the body to cure beriberi or thiamine deficiency. Thiamine pyrophosphate or vitamin B-1 cure beriberi by acting as a co-enzyme in carbohydrate metabolism and for the transketolase in the pentose monophosphate pathway.
Therefore, the recommended daily allowance for thiamine must be followed to prevent or cure thiamine deficiency.