Answer:
When the Europeans first came to America, they did not know how to interact with the various Native American groups that were spread out all over the United States, and the Native Americans also did not know how to respond to the new settlers trying to take over their land. The different responses from each tribe really reflected what their leader was focused on for bettering their tribe.
Native Americans were also vulnerable during the colonial era because they had never been exposed to European diseases, like smallpox, so they didn’t have any immunity to the disease, as some Europeans did. European settlers brought these new diseases with them when they settled, and the illnesses decimated the Native Americans
Though some Native American tribes lived for centuries in the American West, as the white man pushed westward, always wanting more land and resources, they pushed the American Indians out of their way, further populating the West with various tribes. When European settlers arrived on the North American continent at the end of the 15th century, they encountered diverse Native American cultures
Removing Native Americans from their Land. Ohio land cessions. In 1786, the United States established its first Native American reservation and approached each tribe as an independent nation. This policy remained intact for more than one hundred years.