Question

Which type of chromosomal rearrangement accounts for the creation of the gene that encodes the bcr-abl chimeric protein? (for a review of the four different types of chromosomal rearrangements, see hint 1.)?

Answer 1

Translocation is the types of chromosomes that accounts for the creation of the gene that encodes the bcr-abl chimeric protein.Bcr gene is located on chromosome 22. Abl aligns in number 80 segment and encoded on chromosome 9. Only the two types can lead to the fusion of genes from two different chromosomes. Comparison between the number of human genes and those of their animal species has led to a conclusion that human genomes' number of proteins express is more significant than the number of its genes.