The vertex is at (2, 5).
To find the vertex, we first find the axis of symmetry; this is given by
x = -b/2a
For our equation, b = -16 and a = 4:
x = -(-16)/2(4) = 16/8 = 2
We substitute this back into our equation:
y = 4(2)² - 16(2) + 21 = 4(4) - 32 + 21 = 5
Therefore the vertex is at (2, 5).