Final answer:
Nondisjunction during meiosis can result in an abnormal chromosome number in human gametes. If homologous chromosomes fail to separate, two gametes will lack that chromosome and two gametes will have two copies. If sister chromatids fail to separate, one gamete will lack the chromosome, two gametes will have one copy, and one gamete will have two copies.
Step-by-step explanation:
Nondisjunction can occur during either meiosis I or II, resulting in an abnormal chromosome number in human gametes. If homologous chromosomes fail to separate during meiosis I, two gametes will lack that particular chromosome and two gametes will have two copies of the chromosome. If sister chromatids fail to separate during meiosis II, one gamete will lack that chromosome, two gametes will have one copy of the chromosome, and one gamete will have two copies of the chromosome.