1. I believe the correct answer is that he is referring that he already killed his family.
In Shakespeare’s drama “Macbeth”, when Macbeth says to Macduff: "but get thee back, my soul is too much charged with blood of thine already" he refers on a fact that he sent a hitman to kill Macduff’s wife and children (thine is archaic form of yours meaning those of his blood or associated with him).